Coefficient of drug interaction (CDI)?

[Donnieclark]

Hii...


I tested the single and combined effects of two drugs on the protein expression of a gene. I got a weird result if I used the coefficient of drug interaction (CDI) methods i.e. AB/(A*B). Any advice is greatly appreciated.

After normalising the protein expression levels using Western blot to the saline-paired control, i got the following relative averaged expression values..

Thanks..!

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